SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6660274723bb96a34ca7cdd5626c6061070d88b9c65aad969981ba45bcb63b0c' 
  AND token = 'U99zG5ONBnYziAakYUlTzwI0lV/NlDF7YKTnva5KTh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}