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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feb22fdfd3d814c28db35751116ef80ab6f1beff0b26bec8c5f7b1432f198160' 
  AND token = '+muLVseONPuW1BhzMtupcjTZOh9U6Qym8HKBVV/PaUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}