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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e85fa1c109a6fa36f5fc1470dac7cf0b3bcd1f79dead45e5be527d82d07ba4' 
  AND token = 'jR0AZMPF46aCKniiKXkNSOV4mJSlv9Dwza5CDPzYrbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}