SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '897bff43f0f2eb8dd347e43d64da71fb3128f8c38a585f2c9e79055e02e396da' 
  AND token = 'IPfsgMSHzb5sWL1PB3Fg6rTuHGv9fyiHDbhxNKUxNps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}