SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d9c9f052cfd87c6df2559fd2429f898679a73df5f0464197c2c6d3f4cea83ae' 
  AND token = 'Ncf9b+M5CmH9go/sRJYCrs5Iu68vyieiXvtF5NBOmFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}