SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9c1f1584462e01f1ee0371e74d1175837ca722f38b62e117239b12eb9dcbb43' 
  AND token = 'bM2GdhFf+EbVlF5K0RTaf40tBZm00AmJacLc3dhvhlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}