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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2496b6249bb22cf12720d38ed57b77c1c5324ddf0b7633444a011521b97d4c00' 
  AND token = '76EOEMKFGEagtQsm5BD0OVAeDztSORzTVitYMspvKl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}