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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce910c50804e0c27522d5c472bc0cc379fe45d4fe41c23ee66a36ae8fec51b1' 
  AND token = 'WECfa/wILWHJ8cC12TxZoNVAVvx1uBcVKxDw5zm82as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}