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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5b910ea82fa133e075f9111cd382c34d0d2f8150220945edb5aa14f3dc8275' 
  AND token = '/QBvuYE3GaAbbAiMhX/wdXfolLk1JQhKdpt+blJn5Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}