SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a360b40ac78d33a17c84b2dea47120531dac7bf972a57b48999964262d70e4c6' 
  AND token = 'U9NpDExa1R1/87Q3XgSgvDqVlojriFQMimHfQOZ5A6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}