SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8532cd850a4c349c55b5e3cbe576177436122d33ce8cb70671add2c989c1c3' 
  AND token = 'x9bExgoj/MylqEnUKs88wol0oHff96vPtsv7B4cBfnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}