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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f7150f2e78f87bbb9a58d4c6517f41c6ba349992dc65acdd736190a9609b6b6' 
  AND token = '+N1hqQBbLkdKvKHwcdIOeYmj4bvU/9EMoE99duP5Zx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}