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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb7e9da5dc1cfc9daf87e897c88b5183982bcbd074a34e40daf362c30b6a0f21' 
  AND token = 'IaQHbB1HqsW9MTt1w7eIQjRDQxrUES2uUFlKNzPVQa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}