SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289e30e170081e601f4d536fe546d2ca8784eae88198b25b0ed1af0c6d38efe3' 
  AND token = 'gHQB5ilETmo2uWbAGX/kETwiAAfo+8EtY1aD/ZUvV8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}