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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81baf2430ea6b367acc179cb301104fdf70301d1400165fcb45ff52c1a1d07b9' 
  AND token = '44dy9g0xG/652074jjcwFKvEiCPYQYwJsyFWjMpEoNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}