SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b8a4c43fc749cf3ba73652b56e63f28c3c9bb2cca2bffb8d073b0a6537c74d' 
  AND token = 'MBYo1+/4r4WCHukehkXPdAEWhUzwpTn6Koecu33afMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}