SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8413b1b358de499e92aeb1d713dae72f25607397b82c04b2a3cf3aef9f2bafe5' 
  AND token = 'JdlF6rpMAs85tw0AWkxTI6VyVdT5xqT/QXsh8rldEg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}