SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e049abc2e0a69cea083502a1d9945c44deb01d2a22dd1ca00da8fe00e50eb2b7' 
  AND token = 'OXZRl5eM472aZLW2DmKiyHB+C7TbhbOkDlm3aic+VM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}