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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fbb533bc33bcc5ac2c56f3a591791f3de357ce784a8fcdd8aa32974cba046ac' 
  AND token = 'NOP5R6MWbeib289vg0RXAiyna1U3Tnl7Zx6GvREU0uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}