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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defe5ef104590edc91f35c8c1ae8ba64d2f736103e12b7048ba7e53d1bb0bb29' 
  AND token = '8BPiir+wjVUiDQobr3EtQGnqXv8LjZfr4ij+c34BRcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}