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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b14c56a5d8d18a349fabcb9a6c72ddc14bff5ab2deabbd2326598e90c519628' 
  AND token = 'Va8Cr7lkH3VmVopTrqcqmKuxKslMubZC6NyIB+cHJ9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}