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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e844ee4d66aeebd9ad7123221bd9d7467ec0e41ed810c6e016653a8bbb84b44' 
  AND token = 'EYFf1W754lWAVvTTdng2T+rhabh8aYThpLT5x5qf3zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}