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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f46cb1e412b6e3cd9cc106a624744e65c9a3579c503346130332c5988bb014' 
  AND token = 'sJjx8deyXLAGQ6jAMXrbYRsAdpJpOhnirRgdPFUK/tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}