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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080d84c542d679c840c117acf9be7f6e4a9d15f0d907055b0f555e20868af33e' 
  AND token = 'c6yGecMzaPbGrxyq/UQDkeeh+35kIwKzeC5PZy4EVXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}