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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5fa417976a55faa952368ab52116aca217ca2bc83a9357353a45370fc8159ea' 
  AND token = 'TVM545Nct2fESMhN1jePyqBS8vrfSLtZLZ5cD7Voykk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}