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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3723d87ac809678545a56ab9a46aef3b8df3f011f7b193ef98c09ebddcd7de6c' 
  AND token = 'vv9IVUJdRArDejUf+b9SpCi2M2/N7as8vevqkumianQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}