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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4a8327b35e353cfe1a91345d5bbd2f757619c4823d58a067135898dd1acaa1a' 
  AND token = 'NMjwNMm935omR+qRSpu3DhZ7Cy9CeV5nxnp4w5IyRk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}