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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '714fdf3bf7cf75cf0893a842e3a847ea9bf0dce09061bc30dd886f57c1a2f75c' 
  AND token = 'ayZFo6QIMsuWBsjHJjzH33NLBTeN3M4Z6/YBV4bfG/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}