SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    432642, 432643, 432644, 432645, 432646, 
    432647
  ) 
  AND feature_id IN (860, 1013) 
  AND lang_code = 'en'

Query time 0.00207

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "5.84"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 12,
      "rows_produced_per_join": 12,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "3.44",
        "eval_cost": "2.40",
        "prefix_cost": "5.84",
        "data_read_per_join": "9K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`product_id` in (432642,432643,432644,432645,432646,432647)) and (`webmarco`.`cscart_product_features_values`.`feature_id` in (860,1013)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
432642 860 64477
432643 860 64477
432644 860 64477
432645 860 66121
432646 860 66121
432647 860 66121
432642 1013 64561
432643 1013 64562
432644 1013 64563
432645 1013 64561
432646 1013 64562
432647 1013 64563