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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4283aac658e345d2f6fbb8f5a125aa6e735c0591f98fc1468c8ab8c1ef09b89f' 
  AND token = 'o0n1xAh0yLrM2rdGlxkUGoZ0PMc4eihlDyJKoK1X+eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}