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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b4ad42ef500906b377dfe7337d6c0175bc447d97af2cbe1a6e6bb911fed102' 
  AND token = 'QlZiZ0PO5KQr09FamJbj/gso/KZPGT8+ON8yQCAUZXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}