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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a967607cb8467be511b1da06a85f9444f5c9938661d6061bcb8957ae8f401e09' 
  AND token = 'sRKTbxtC4xdn6xEQu1KmRw4wbWuH7e3cqjmgHn25Pno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}