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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8849dc94ab220674f051e1e4e2365199ead66ccd2250d90361613d60c00551a7' 
  AND token = 'eCp1lJq/rJpSXtuYxEVgtRRL8siyAlXMH60f3wHWoL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}