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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6f0d1037e1e3305586b4d1918da95716579d2a1fdce8f89153c2704a0a1f51' 
  AND token = 'c+x8FIX0IsJLNxMx5ZI6KF8M9fOQ5VirbYG48eqw9T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}