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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0c3569720fa3e0bea267fa92ab2742ac99713b5b4e917c0569e44698a2ab39' 
  AND token = 'ZYFa3pLG4S3Vt9o1j8kf0S26gWy7gPsaDxnUGXdfrYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}