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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a053ee82cf2404a4abc1a55f1f1f020b8a897c03ab32c42abc112f070211364' 
  AND token = 'tOshA+hCOo4LXz/bNnCd+ze4uvmSc3VjrKSBsRX/Tbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}