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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd30542c154b106012a2dabaa654b9d94f19503d9ed985c277e6f0329a3ab79' 
  AND token = '8hlAN6XRMmeLroWZvA8kC0fHtgDPFhGlNubMPqAxdWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}