SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7787bd6b03b02a35fd6852bd7603a049484691e031e661bb54282d105f407b9' 
  AND token = '61hgPOVi9/SjYPPs2lAjFek/CSDiJ493hQiUPHKF5i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}