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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d9e6169d0084bdf253c67175247dd8e170467da11065690a47afa457d83f02' 
  AND token = 'XkrHN4n3BRBOXiAnX0P1O+6i/1apOcpTS3SKXrXQ8N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}