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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354000f2f1aedee827205a160b872cc840b3d584092e48bb4d87ec12e901b45c' 
  AND token = 'LDsnjxSHchrstN5KZ8skOlv9LQZqz9bx2Mh5LOj92GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}