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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6270c45561e100ebe5a6be4325fed738648fd1e289f25e1e7c37a299a92e08cc' 
  AND token = 'AMRWqSolm1Y1TuOCpDVbaApoKR2cylHQ6qjWaA+F2Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}