SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00e104e7ff906be471bc77cdaa2e6b737774ed8c2bd4335d8010ce24206f522' 
  AND token = 'wX3Wz9AS2vDZ9XbrB4zV1f1Nb9F0O8OBiCvgjr2TEa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}