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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f651d651c0fa180f043a3ef41dcc3b91bedacc1aa198f374148a1c53f2b61423' 
  AND token = '777xk/+ss1RkoAT1aSqvkWQENLAYp7wsU2Eyrw2URy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}