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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f87216ff17a49e9da81a4a1f037753e266b4c7685ea261047f029eb71aac2641' 
  AND token = '3xb7ELfCUzMo/XxVd9HeZoEChkgUXUIluAQ8DoCCzck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}