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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73efa3dc4a6901b79185880ff24d80291507dae175329ddf330a4b21309f1382' 
  AND token = '74dy7y5lzttNBguhr1JTsW45y0Ku+0cPFmELPL0a6cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}