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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3657c7ddad1ffbe11b231f4644ddb47e958636abf71e4f08090c800840086b26' 
  AND token = '48SgajNRx0CgPE9F91LqZIrdhDhNA2QT9zXGhsn1AS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}