SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81cdbf4c530017feb283330e7c23d7d7d95b88419dbc772ca810ccc66866110' 
  AND token = 'bNQqLAWuTtg7nCK6jmD0CFQwUnjnofKmO/bNdVbjjuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}