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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6b960e6a7ddceb956a7248ed54e20e630e14654b0e4e696aa823809a986753d' 
  AND token = '3s61l6H/F79N7avyc+IZPrGmvZPaojdj5/z8Tqkenas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}