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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c05fb3fafc503f464979f24f75866b82eb8858a40289b1120fcc51189f2fe4b' 
  AND token = 'QkuAQifR4biyw+b9g9ejrlYsv0UKssYCCXv0cYWZ2+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}