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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86400ed78b0b77e7b37a68d6c241bdb12c364ffea5b18f06ee33dd3f3cf2fc4b' 
  AND token = 'YynkgY57vA8E9X/ic7RqxzXMV14C6GzMPr+VtCwhreU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}